• 

  减少透析器凝血现象发生^[1]

• 

  提高透析效率与清除率^[2]

• 

  改善酸碱平衡^[3]

• 

  减少炎症与氧化应激^[4]

• 

  血流动力学稳定性好^[3]

 

文献：

[1]Tai DJ, Leung K, Ravani P, Quinn RR, Scott-Douglas N, MacRae JM; Alberta Kidney Disease Network. The effect of citrate dialysate on intradialytic heparin dose in haemodialysis patients: study design of a randomised controlled trial. BMC Nephrol. 2015 Aug 25;16:147. doi: 10.1186/s12882-015-0144-z. PMID: 26303208; PMCID: PMC4548909.

[2]Lee JY, Kim KS, Cho HJ, Joo Y, Lee YJ, Park JH, Jo YI. Switching from acetate to citrate dialysate in a central concentrate delivery system for high-volume online hemodiafiltration: a retrospective cohort study. Ren Fail. 2024 Dec;46(2):2398709. doi: 10.1080/0886022X.2024.2398709. Epub 2024 Sep 9. PMID: 39252176; PMCID: PMC11389627.

[3]王越, 李梦婷, 谢庆磊, 等. 不同缓冲剂碳酸氢盐透析液在无肝素血液透析患者中的应用研究[J]. 临床肾脏病杂志, 2023, 23(7): 536-540.

[4]Grundström G, Christensson A, Alquist M, Nilsson LG, Segelmark M. Replacement of acetate with citrate in dialysis fluid: a randomized clinical trial of short term safety and fluid biocompatibility. BMC Nephrol. 2013 Oct 9;14:216. doi: 10.1186/1471-2369-14-216. PMID: 24103587; PMCID: PMC4124727.